KMID : 0895820050150020091
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Journal of Oriental Rehabilitation Medicine 2005 Volume.15 No. 2 p.91 ~ p.104
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Effects of Herbal Acupuncture (Angelica gigas, Astragalus membranaceus) on Diet, Serum Lipid Metabolism and ALT in Obese Rats Induced by High Fat Diet
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Shin Mi-Suk
Choi Jin-Bong
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Abstract
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Objectives: This study was performed to investigate the effect of herbal acupuncture(Angelica gigas, Astragalus membranaceus) at Chung-wan(CV12) and Chok-Samni(ST36) on weight gain, food intake, food efficiency, serum of lipid concentrations, liver function and HDL-cholesterol to total cholesterol ratio of rats fed high fat diet for 5 weeks.
Methods: Experimental groups were divided into normal group, high fat diet group(Control), high fat diet and Angelica gigas herbal acupuncture at CV12 and ST36 treated group(HA-1), high fat diet and Astragalus membranaceus herbal acupuncture at CV12 and ST36 treated group(HA-2), high fat diet and Angelica gigas plus Astragalus membranaceus herbal acupuncture at CV12 and ST36 treated group(HA-3). Herbal acupuncture was bilaterally treated at the level of 16.7 ul/kg body weight per day.
Results: Body weight were significantly decreased on 15th and 20th day in HA-1, HA-2, and decresed on 25th and 30th day in all the groups. Food intake were increased on 20th day and after were decreased on 30th day in HA-1 and HA-2. And food intake of HA-3 were decreased on 10th day and after were increased on 20th and 25th day. Total cholesterol, LDL-cholesterol, triglyceride and ALT were significantly decreased in HA-1, HA-2 and HA-3 groups compared with control group. HDL-cholesterol to total cholesterol ratio were significantly increased in HA-1, HA-2 and HA-3 groups compared with control group. And food efficiency were significantly decreased in HA-1 and HA-3 groups compared with control group. Especially HDL-cholesterol were increased in HA-1 group.
Conclusions: Herbal acupuncture using Angelica gigas and Astragalus membranaceus at CV12 and ST36 can manage obesity by controlling body weight, food intake and food efficiency ratio.
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KEYWORD
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Herbal acupuncture, Obesity, Angelica gigas, Astragalus membranaceus, Chung-wan(CV12), Chok-Samni(ST36), High fat diet
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