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KMID : 0895820050150020091
Journal of Oriental Rehabilitation Medicine
2005 Volume.15 No. 2 p.91 ~ p.104
Effects of Herbal Acupuncture (Angelica gigas, Astragalus membranaceus) on Diet, Serum Lipid Metabolism and ALT in Obese Rats Induced by High Fat Diet
Shin Mi-Suk

Choi Jin-Bong
Abstract
Objectives: This study was performed to investigate the effect of herbal acupuncture(Angelica gigas, Astragalus membranaceus) at Chung-wan(CV12) and Chok-Samni(ST36) on weight gain, food intake, food efficiency, serum of lipid concentrations, liver function and HDL-cholesterol to total cholesterol ratio of rats fed high fat diet for 5 weeks.

Methods: Experimental groups were divided into normal group, high fat diet group(Control), high fat diet and Angelica gigas herbal acupuncture at CV12 and ST36 treated group(HA-1), high fat diet and Astragalus membranaceus herbal acupuncture at CV12 and ST36 treated group(HA-2), high fat diet and Angelica gigas plus Astragalus membranaceus herbal acupuncture at CV12 and ST36 treated group(HA-3). Herbal acupuncture was bilaterally treated at the level of 16.7 ul/kg body weight per day.

Results: Body weight were significantly decreased on 15th and 20th day in HA-1, HA-2, and decresed on 25th and 30th day in all the groups. Food intake were increased on 20th day and after were decreased on 30th day in HA-1 and HA-2. And food intake of HA-3 were decreased on 10th day and after were increased on 20th and 25th day. Total cholesterol, LDL-cholesterol, triglyceride and ALT were significantly decreased in HA-1, HA-2 and HA-3 groups compared with control group. HDL-cholesterol to total cholesterol ratio were significantly increased in HA-1, HA-2 and HA-3 groups compared with control group. And food efficiency were significantly decreased in HA-1 and HA-3 groups compared with control group. Especially HDL-cholesterol were increased in HA-1 group.

Conclusions: Herbal acupuncture using Angelica gigas and Astragalus membranaceus at CV12 and ST36 can manage obesity by controlling body weight, food intake and food efficiency ratio.
KEYWORD
Herbal acupuncture, Obesity, Angelica gigas, Astragalus membranaceus, Chung-wan(CV12), Chok-Samni(ST36), High fat diet
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